Abstract
Background: Fever, is known as pyrexia, may occur due to infection, inflammation, or anytissue damage and disease states. Normally, the infected or damaged tissue initiates the enhanced formationof pro-inflammatory mediators like cytokines which further increases the synthesis of prostaglandinE2 (PgE2) near the hypothalamic area and thereby trigger the hypothalamus to elevate the body temperature.
Objective: Antipyretics are the agents which reduce the elevated body temperature. The most commonlyused antipyretic agent, paracetamol, may be fatal due to its side effects.
Methods: In this review paper, Chemical Abstracts, Google Scholar, PubMed, and Science Direct werethe sources for the published article to collect information regarding antipyretic activity.
Results: This review compiles the antipyretic plants that may be useful to treat fever due to variousdiseases.
Conclusion: These medicinal plants could be good alternatives for traditional allopathic antipyretics.
Keywords: Fever, pyrexia, antipyretic plants, NSAIDS, antibiotics, flavivirus.
Graphical Abstract
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Current Bioactive Compounds
Title:Antipyretic Plants: An Updated Review
Volume: 16 Issue: 1
Author(s): Vandana Garg and Rohit Dutt*
Affiliation:
- School of Medical and Allied Sciences, G. D. Goenka University, Gurugram 122103,India
Keywords: Fever, pyrexia, antipyretic plants, NSAIDS, antibiotics, flavivirus.
Abstract:
Background: Fever, is known as pyrexia, may occur due to infection, inflammation, or anytissue damage and disease states. Normally, the infected or damaged tissue initiates the enhanced formationof pro-inflammatory mediators like cytokines which further increases the synthesis of prostaglandinE2 (PgE2) near the hypothalamic area and thereby trigger the hypothalamus to elevate the body temperature.
Objective: Antipyretics are the agents which reduce the elevated body temperature. The most commonlyused antipyretic agent, paracetamol, may be fatal due to its side effects.
Methods: In this review paper, Chemical Abstracts, Google Scholar, PubMed, and Science Direct werethe sources for the published article to collect information regarding antipyretic activity.
Results: This review compiles the antipyretic plants that may be useful to treat fever due to variousdiseases.
Conclusion: These medicinal plants could be good alternatives for traditional allopathic antipyretics.
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Cite this article as:
Garg Vandana and Dutt Rohit *, Antipyretic Plants: An Updated Review, Current Bioactive Compounds 2020; 16 (1) . https://dx.doi.org/10.2174/1573407215666190401151844
| DOI https://dx.doi.org/10.2174/1573407215666190401151844 | Print ISSN 1573-4072 |
| Publisher Name Bentham Science Publisher | Online ISSN 1875-6646 |
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